Background: Silver nanoparticles (AgNPs) was recommended in medicine and veterinary medicine fields, and can be used as drugs for treatment of some diseases. Aim: the toxicity of nanosilver is not well known, it is essential to examine its safety. The experimental albino rats were divided into five groups , each group comprising of ten rats, after adaptation in the animal houses in Faulty of Vet. Medicine Suez Cana University for one week. The groups named as N1, 2, 3, 4 and 5. Group N1, was called control group and was gives deionized water. Blood samples were collected at the end of experiment; serum samples were separated for determination the values of IL-Lβ, IL-2, IL-6, IL-10 and TNF-α. Ag-NPs administration showed a variable significant increase in the levels of Il-Lβ, IL-2, IL-6, IL10 and TNF- α . Conclusion : Nanoparticles induce inflammatory immune responses at lower concentrations and chemokines are the major cytokines induced at early stage of exposure to silver nanoparticles..
Ashour, I., Saleh, S., Shalhy, A. ,., Ibrahim, E., & Doiwdar, M. (2017). Silver Nanoparticles Effect on Cytokines in Rat. Biochemistry Letters, 13(1), 172-182. doi: 10.21608/blj.2017.47608
MLA
I. Ashour; S, Saleh; A. , Shalhy; E. Ibrahim; M., Doiwdar. "Silver Nanoparticles Effect on Cytokines in Rat". Biochemistry Letters, 13, 1, 2017, 172-182. doi: 10.21608/blj.2017.47608
HARVARD
Ashour, I., Saleh, S., Shalhy, A. ,., Ibrahim, E., Doiwdar, M. (2017). 'Silver Nanoparticles Effect on Cytokines in Rat', Biochemistry Letters, 13(1), pp. 172-182. doi: 10.21608/blj.2017.47608
VANCOUVER
Ashour, I., Saleh, S., Shalhy, A. ,., Ibrahim, E., Doiwdar, M. Silver Nanoparticles Effect on Cytokines in Rat. Biochemistry Letters, 2017; 13(1): 172-182. doi: 10.21608/blj.2017.47608
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